Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 51726
Gene Symbol: DNAJB11
DNAJB11 		0.310 Biomarker disease GENOMICS_ENGLAND DNAJB11-associated disease is a phenotypic hybrid of ADPKD and ADTKD, characterized by normal-sized cystic kidneys and progressive interstitial fibrosis resulting in late-onset ESRD. 29706351 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.300 Biomarker disease RGD Changes of adiponectin and its receptors in rats following chronic renal failure. 24028144 2014
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.300 Therapeutic disease RGD Carbonic adsorbent AST-120 retards progression of renal failure by additive effect with ACEI and protein restriction diet. 14586729 2003
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.300 Biomarker disease RGD Oral sorbent AST-120 increases renal NO synthesis in uremic rats. 18089446 2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.300 Biomarker disease RGD Only animals from the 1WIK group developed severe chronic renal failure, glomerulosclerosis, interstitial fibrosis, and upregulation of transforming growth factor-beta(1) (TGF-beta(1)) gene, which was associated with increased TGF-beta(1) protein expression in tubular epithelial cells, arterioles, and in areas of mononuclear interstitial cell infiltrate. 10919844 2000
Entrez Id: 5741
Gene Symbol: PTH
PTH 		0.300 Biomarker disease RGD Two novel vitamin D receptor modulators with similar structures exhibit different hypercalcemic effects in 5/6 nephrectomized uremic rats. 23548814 2013
Entrez Id: 9365
Gene Symbol: KL
KL 		0.300 Biomarker disease RGD This is the first report showing the expression of the klotho gene in the kidney is regulated under sustained circulatory stress such as long-term hypertension, diabetes mellitus, and chronic renal failure. 9731228 1998
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.290 Biomarker disease RGD Expression of monocyte chemoattractant protein-1 in proximal tubular epithelial cells in a rat model of progressive kidney failure. 12080327 2002
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.290 Therapeutic disease RGD Effect of exercise on cardiac tissue oxidative and inflammatory mediators in chronic kidney disease. 18797164 2009
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.280 Biomarker disease RGD Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase. 22031851 2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.280 Biomarker disease RGD Multiple antioxidants and L-arginine modulate inflammation and dyslipidemia in chronic renal failure rats. 20199183 2010
Entrez Id: 1234
Gene Symbol: CCR5
CCR5 		0.260 Biomarker disease RGD Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats. 19535570 2009
Entrez Id: 57817
Gene Symbol: HAMP
HAMP 		0.260 Biomarker disease RGD Erythropoietin regulates intestinal iron absorption in a rat model of chronic renal failure. 20631677 2010
Entrez Id: 1535
Gene Symbol: CYBA
CYBA 		0.250 Biomarker disease RGD Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure. 19420110 2009
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.240 Biomarker disease RGD Renal endothelin gene expression is increased in remnant kidney and correlates with disease progression. 8441230 1993
Entrez Id: 51094
Gene Symbol: ADIPOR1
ADIPOR1 		0.230 Biomarker disease RGD Changes of adiponectin and its receptors in rats following chronic renal failure. 24028144 2014
Entrez Id: 4842
Gene Symbol: NOS1
NOS1 		0.230 Biomarker disease RGD Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat. 17200156 2007
Entrez Id: 4842
Gene Symbol: NOS1
NOS1 		0.230 Therapeutic disease RGD [Effects of shenshuai II recipe on the protein expressions of Ang II and nNOS in chronic renal failure rats' nephridial tissue]. 23185775 2012
Entrez Id: 6352
Gene Symbol: CCL5
CCL5 		0.220 Biomarker disease RGD Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats. 19535570 2009
Entrez Id: 3931
Gene Symbol: LCAT
LCAT 		0.220 Biomarker disease RGD ACAT inhibition reverses LCAT deficiency and improves plasma HDL in chronic renal failure. 15280162 2004
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.210 Biomarker disease RGD [Curative machanism of Shenle capsule on 5/6 nephrectomy rats]. 15506291 2004
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		0.210 Biomarker disease RGD High-calorie diet with moderate protein restriction prevents cachexia and ameliorates oxidative stress, inflammation and proteinuria in experimental chronic kidney disease. 20820841 2010
Entrez Id: 79602
Gene Symbol: ADIPOR2
ADIPOR2 		0.210 Biomarker disease RGD Changes of adiponectin and its receptors in rats following chronic renal failure. 24028144 2014
Entrez Id: 1536
Gene Symbol: CYBB
CYBB 		0.210 Biomarker disease RGD Iron and oxidative stress in renal insufficiency. 15550752 2005
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.210 Therapeutic disease RGD Epoetin delta as an antifibrotic agent in the remnant kidney rat: a possible role for transforming growth factor beta and hepatocyte growth factor. 20424483 2010